Reference Materials

Value assignment of nutrient concentrations in five standard reference materials and six reference materials.

A number of food-matrix reference materials (RMs) are available from the National Institute of Standards and Technology (NIST) and from Agriculture Canada through NIST. Most of these materials were originally value-assigned for their elemental composition (major, minor, and trace elements), but no additional nutritional information was provided. Two of the materials were certified for selected ...

Performance criteria for reference measurement procedures and reference materials.

The concept of metrological traceability of measurement results to property values assigned to measurement standards of higher metrological order or to the International System of Units (SI) through sequential calibrations, using reference materials and reference measurement procedures, plays a key role in ensuring that end user measurement procedures perform at an acceptable level in the clini...

Challenges in Providing Standard Reference Materials

The NIST Analytical Chemistry Division has supplied transmittance verification and wavelength calibration standard reference materials (SRMs) specialized to the needs of chemical and pharmaceutical spectrophotometric analysis since 1970. Growing demand for UV/visible standards stems from the increasingly routine use of spectrophotometers for pharmaceutical quality control and from the escalatio...

Development of Multi-Purpose Biological Reference Materials

Universal RNA reference materials for gene expression.

A workshop entitled "Metrology and Standards Needs for Gene Expression Technologies: Universal RNA Standards" was held in March 2003 to define the requirements for standardizing RNA-based molecular assays, specifically microarray and quantitative reverse-transcriptase-PCR technologies. NIST sponsored the workshop, and participants represented government, industry, academia, and clinic. Workshop...